Clinical spectrum of endemic leptospirosis in relation to cytokine response.

ABSTRACT:

Objectives

To describe the clinical spectrum and the cytokine response of leptospirosis patients in an endemic setting of Sri Lanka.

Methods

Patients presenting to the university teaching hospital, Anuradhapura, Sri Lanka with a leptospirosis-compatible illness were recruited over a period of 12 months starting from June 2012. Daily clinical and biochemical parameters of the patients were prospectively assessed with a follow-up of 14 days after discharge. A magnetic bead-based multiplex cytokine kit was used to detect 17 cytokines.

Results

Of the 142 clinically suspected leptospirosis patients recruited, 47 were confirmed and, 29 cases were labeled as "probable." Thrombocytopenia and leukocytosis were observed at least once during the hospital stay among 76(54%) and 3

SUBMITTER: Dahanayaka NJ 

PROVIDER: S-EPMC8654203 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature