A comparison of three strategies to reduce the burden of osteoarthritis: A population-based microsimulation study.

ABSTRACT:

Objectives

The purpose of this study was to compare three strategies for reducing population health burden of osteoarthritis (OA): improved pharmacological treatment of OA-related pain, improved access to joint replacement surgery, and prevention of OA by reducing obesity and overweight.

Methods

We applied a validated computer microsimulation model of OA in Canada. The model simulated a Canadian-representative open population aged 20 years and older. Variables in the model included demographics, body mass index, OA diagnosis, OA treatment, mortality, and health-related quality of life. Model parameters were derived from analyses of national surveys, population-based administrative data, a hospital-based cohort study, and the literature. We compared 8 what-if intervention sce

SUBMITTER: Kopec JA 

PROVIDER: S-EPMC8654220 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature