Germ cell apoptosis is critical to maintain Caenorhabditis elegans offspring viability in stressful environments.

ABSTRACT: Maintaining reproduction in highly variable, often stressful, environments is an essential challenge for all organisms. Even transient exposure to mild environmental stress may directly damage germ cells or simply tax the physiology of an individual, making it difficult to produce quality gametes. In Caenorhabditis elegans, a large fraction of germ cells acts as nurse cells, supporting developing oocytes before eventually undergoing so-called physiological germ cell apoptosis. Although C. elegans apoptosis has been extensively studied, little is known about how germline apoptosis is influenced by ecologically relevant environmental stress. Moreover, it remains unclear to what extent germline apoptosis contributes to maintaining oocyte quality, and thus offspring viability, in such conditio

SUBMITTER: Fausett S 

PROVIDER: S-EPMC8654231 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature