Regional anesthesia and cancer recurrence in patients with late-stage cancer: a systematic review and meta-analysis.

ABSTRACT:

Background

Whether regional anesthesia may help to prevent disease recurrence in cancer patients is still controversial. The stage of cancer at the time of diagnosis is a key factor that defines prognosis and is one of the most important sources of heterogeneity for the treatment effect. We sought to update existing systematic reviews and clarify the effect of regional anesthesia on cancer recurrence in late-stage cancer patients.

Methods

Medline, Embase, and Cochrane Library were searched from inception to September 2020 to identify randomized controlled trials (RCTs) and cohort studies that assessed the effect of regional anesthesia on cancer recurrence and overall survival (OS) compared with general anesthesia. Late-stage cancer patients were primarily assessed according

SUBMITTER: Zhang YL 

PROVIDER: S-EPMC8654444 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature