Effects of SPARCL1 on the proliferation and differentiation of sheep preadipocytes.

ABSTRACT: Important candidate genes that regulate lipid metabolism have the potential to increase the content of intramuscular fat (IMF) and improve meat quality. Secreted protein acidic and rich in cysteine like 1(SPARCL1) is a secreted glycoprotein with important physiological functions and is involved in the proliferation and differentiation of various cells. However, the role of the SPARCL1 gene in sheep preadipocytes and its regulatory mechanism is still unclear. In this study, we explored the effect of SPARCL1 on the proliferation and differentiation of sheep preadipocytes. The results showed that the expression level of the SPARCL1 gene is higher in fat tissue than in other tissues, and the gene was significantly increased on the 6^th day of preadi

SUBMITTER: Xiao C 

PROVIDER: S-EPMC8654481 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature