Multiple Survival Outcome Prediction of Glioblastoma Patients Based on Multiparametric MRI.

ABSTRACT:

Purpose

Construction of radiomics models for the individualized estimation of multiple survival stratification in glioblastoma (GBM) patients using the multiregional information extracted from multiparametric MRI that could facilitate clinical decision-making for GBM patients.

Materials and methods

A total of 134 eligible GBM patients were selected from The Cancer Genome Atlas. These patients were separated into the long-term and short-term survival groups according to the median of individual survival indicators: overall survival (OS), progression-free survival (PFS), and disease-specific survival (DSS). Then, the patients were divided into a training set and a validation set in a ratio of 2:1. Radiomics features (n = 5,152) were extracted from multiple regions of the GBM u

SUBMITTER: Wang B 

PROVIDER: S-EPMC8655336 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature