Association Between Cadmium Exposure and Liver Function in Adults in the United States: A Cross-sectional Study.

ABSTRACT:

Objectives

Cadmium is widely used, leading to extensive environmental and occupational exposure. Unlike other organs, for which the harmful and carcinogenic effects of cadmium have been established, the hepatotoxicity of cadmium remains unclear. Some studies detected correlations between cadmium exposure and hepatotoxicity, but others concluded that they were not associated. Thus, we investigated the relationship between cadmium and liver damage in the general population.

Methods

In total, 11 838 adult participants from National Health and Nutrition Examination Survey 1999-2015 were included. Urinary cadmium levels and the following liver function parameters were measured: alanine aminotransferase (ALT), aspartate aminotransferase (AST), gamma glutamyl transferase (GGT), tot

SUBMITTER: Hong D 

PROVIDER: S-EPMC8655368 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature