Comparison of Characteristics, Follow-up and Outcomes of Active Surveillance for Prostate Cancer According to Ethnicity in the GAP3 Global Consortium Database.

ABSTRACT:

Background

Studies of active surveillance (AS) for prostate cancer (PCa) have focussed predominantly on Caucasian populations. Little is known about the experience of Asian men, while suitability for men of African descent has been questioned.

Objective

To compare baseline characteristics, follow-up, and outcomes for men on AS for PCa, according to ethnicity.

Design setting and participants

The study cohort included 13 centres from the GAP3 consortium that record ethnicity (categorised broadly as Caucasian/white, African/Afro-Caribbean/black, Asian, mixed/other, and unknown). Men with biopsy grade group >2, prostate-specific antigen (PSA) >20 ng/ml, T stage ≥cT3, or age >80 yr were excluded.

Outcome measurements and statistical analysis

Clinical characteristics

SUBMITTER: Beckmann K 

PROVIDER: S-EPMC8655390 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature