Comparison of in vitro fertilization cycles in couples with human immunodeficiency virus type 1 infection versus noninfected couples through a retrospective matched case-control study.

ABSTRACT:

Objective

To compare in vitro fertilization (IVF) outcomes in couples in which at least one partner is human immunodeficiency virus (HIV) positive with that of couples in which neither partner is HIV-positive.

Design

Retrospective matched case-control study.

Setting

Fertility center at Tenon Hospital, Paris, France.

Patients

A total of 179 IVF cycles in couples infected with HIV-1 and 179 IVF cycles in control couples.

Interventions

Ovarian stimulation, oocytes retrieval, IVF (standard and microinjection), embryo transfer, pregnancy, and live birth follow-up.

Main outcome measures

Live birth rate and IVF outcomes.

Results

The first comparison between HIV and non-HIV couples showed poorer outcomes in the HIV group (higher administered gonado

SUBMITTER: Vianna CA 

PROVIDER: S-EPMC8655394 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature