Toxicity and Efficacy After Adjuvant Vaginal Brachytherapy Using 30 Gy in 6 Fractions for Stages I and II Endometrial Cancer.

ABSTRACT:

Purpose

This study aimed to evaluate outcomes and toxicity in patients with endometrial cancer per our institutional adjuvant vaginal cuff brachytherapy (VBT) fractionation scheme.

Methods and materials

We identified women with International Federation of Gynecology and Oncology stages I and II endometrial cancer who underwent surgical staging and adjuvant high-dose-rate VBT without external beam radiation. All patients received 30 Gy in 6 fractions to the upper one-third of the vagina, prescribed to a depth of 5 mm and delivered twice weekly. Toxicities were prospectively elicited at each follow up, and rates of recurrence and survival were retrospectively assessed.

Results

We identified 247 eligible patients treated between 1992 and 2018 with a median follow up of 5

SUBMITTER: Arden JD 

PROVIDER: S-EPMC8655421 | biostudies-literature | 2021 Nov-Dec

REPOSITORIES: biostudies-literature