Dosimetric Comparison of Proton Versus Photon Radiosurgery for Treatment of Pituitary Adenoma.

ABSTRACT:

Purpose

To compare the dosimetric differences in stereotactic radiosurgery between use of passively scattered protons (PSRS) versus photons (XSRS) for pituitary adenomas.

Methods and materials

Nine patients with pituitary adenomas were selected among patients receiving single-fraction proton stereotactic radiosurgery (PSRS) between 2016 and 2017. These cases were replanned with XSRS using volumetric-modulated arc therapy with 2.5 mm and 5 mm multileaf collimators (2.5XSRS and 5XSRS, respectively). PSRS was planned with a dedicated single scattering stereotactic proton unit delivered via 3 equally or unequally weighted isocentric fields. XSRS plans were created with optimization to spare organs at risk. Plans were generated using the original total treatment dose delivered in

SUBMITTER: Sud S 

PROVIDER: S-EPMC8655425 | biostudies-literature | 2021 Nov-Dec

REPOSITORIES: biostudies-literature