Linear Dichroism Activity of Chiral Poly(<i>p</i>-Aryltriazole) Foldamers.

ABSTRACT: Controllable higher-order assembly is a central aim of macromolecular chemistry. An essential challenge to developing these molecules is improving our understanding of the structures they adopt under different conditions. Here, we demonstrate how flow linear dichroism (LD) spectroscopy is used to provide insights into the solution structure of a chiral, self-assembled fibrillar foldamer. Poly(para-aryltriazole)s fold into different structures depending on the monomer geometry and variables such as solvent and ionic strength. LD spectroscopy provides a simple route to determine chromophore alignment in solution and is generally used on natural molecules or molecular assemblies such as DNA and M13 bacteriophage. In this contribution, we show that LD spectroscopy is a powerful tool in

SUBMITTER: Carter JG 

PROVIDER: S-EPMC8656205 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature