Development and validation of a nomogram for predicting varices needing treatment in compensated advanced chronic liver disease: A multicenter study.

ABSTRACT:

Background

Only a small proportion of patients with compensated advanced chronic liver disease (cACLD) had varices needing treatment (VNT) after recommended esophagogastroduodenoscopy (EGD) screening. We aimed to create a non-invasive nomogram based on routine tests to detect VNT in cACLD patients.

Methods

The training cohort included 162 cACLD patients undergoing EGD in a university hospital, between January 2014 and September 2019. A nomogram was developed based on the independent predictors of VNT, selected using a multivariate logistic regression analysis. Thirty-three patients from eight university hospitals were prospectively enrolled as validation cohort between December 2018 and December 2019.

Results

The prevalence of VNT was 32.7% (53/162) and 39.4% (13/33)

SUBMITTER: Wang J 

PROVIDER: S-EPMC8656326 | biostudies-literature | 2021 Nov-Dec

REPOSITORIES: biostudies-literature