Effect of Pincer Methylation on the Selectivity and Activity in (PNP)Cobalt-Catalyzed C(sp²)-H Borylation.

ABSTRACT: Cobalt complexes supported by a tetramethylated PNP pincer ligand (Me₄ ^iPrPNP = 2,6-(ⁱPr₂PCMe₂)₂(C₅H₃N)) have been synthesized and structurally characterized. Examples include cobalt(I)-choride, -methyl, -aryl and -benzofuranyl derivatives. The performance of these compounds was evaluated in the catalytic borylation of fluorinated arenes using B₂Pin₂ as the boron source. While P-C bond cleavage, a known deactivation pathway in [(PNP)Co]-catalyzed borylation was suppressed, the overall activity and selectivity of the borylation of fluoroarenes was reduced as compared to the previously reported [(PNP)Co] catalyst lacking isopropylene spacers. Stoichiometric reactions support an incre

SUBMITTER: Lee B 

PROVIDER: S-EPMC8656436 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature