Ontology highlight
ABSTRACT:
SUBMITTER: Maillet D
PROVIDER: S-EPMC8656805 | biostudies-literature | 2021 Nov
REPOSITORIES: biostudies-literature
Maillet Denis D Allioli Nathalie N Péron Julien J Plesa Adriana A Decaussin-Petrucci Myriam M Tartas Sophie S Sajous Christophe C Ruffion Alain A Crouzet Sébastien S Freyer Gilles G Vlaeminck-Guillem Virginie V
Cancers 20211129 23
HER2-dependent signaling may support the development of metastatic castration-resistant prostate cancer (mCRPC) by activating androgen receptor signaling through ligand-independent mechanisms. From 41 mCRPC patients (including 31 treated with Androgen Receptor Signaling Inhibitors [ARSI]), Circulating Tumor Cells (CTCs) were prospectively enriched with AdnaTest platform and analyzed with a multiplexed assay for <i>HER2</i> and <i>AR-V7</i> mRNA expression. Then, we evaluated the impact of HER2 e ...[more]