Sleep fragmentation and incidence of congestive heart failure: the Sleep Heart Health Study.

ABSTRACT:

Study objectives

Sleep fragmentation (SF) has been reported to be associated with cardiovascular risk. The aim of this study was to explore the relationship between SF and congestive heart failure (CHF).

Methods

A total of 4,887 participants (2,256 males and 2,631 females; mean age of 63.6 ± 11.0 years) from the Sleep Heart Health Study were included in this study. Incident CHF was defined as the first occurrence of CHF between baseline in-home polysomnography (PSG) and the end of follow-up. Objective assessments for SF, including sleep fragmentation index (SFI), arousal index (ArI), sleep efficiency (SE), and wake after sleep onset (WASO), were determined based on in-home PSG records. Multivariate Cox regression analysis was used to investigate the relationship between SF a

SUBMITTER: Yan B 

PROVIDER: S-EPMC8656916 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature