Rho-Kinase as a Target for Cancer Therapy and Its Immunotherapeutic Potential.
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ABSTRACT:
SUBMITTER: Kim S
PROVIDER: S-EPMC8657458 | biostudies-literature | 2021 Nov
REPOSITORIES: biostudies-literature
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Rho-Kinase as a Target for Cancer Therapy and Its Immunotherapeutic Potential.
Kim Seohyun S Kim Seong A SA Han Jihoon J Kim In-San IS
International journal of molecular sciences 20211129 23
Cancer immunotherapy is fast rising as a prominent new pillar of cancer treatment, harnessing the immune system to fight against numerous types of cancer. Rho-kinase (ROCK) pathway is involved in diverse cellular activities, and is therefore the target of interest in various diseases at the cellular level including cancer. Indeed, ROCK is well-known for its involvement in the tumor cell and tumor microenvironment, especially in its ability to enhance tumor cell progression, migration, metastasis ...[more]
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