Exploiting Structural Modelling Tools to Explore Host-Translocated Effector Proteins.

ABSTRACT: Oomycete and fungal interactions with plants can be neutral, symbiotic or pathogenic with different impact on plant health and fitness. Both fungi and oomycetes can generate so-called effector proteins in order to successfully colonize the host plant. These proteins modify stress pathways, developmental processes and the innate immune system to the microbes' benefit, with a very different outcome for the plant. Investigating the biological and functional roles of effectors during plant-microbe interactions are accessible through bioinformatics and experimental approaches. The next generation protein modeling software RoseTTafold and AlphaFold2 have made significant progress in defining the 3D-structure of proteins by utilizing novel machine-learning algorithms using amino acid sequences as

SUBMITTER: Amoozadeh S 

PROVIDER: S-EPMC8657640 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature