Determinants and Dynamic Changes of Generic Quality of Life in Human Bladder Cancer Patients.

ABSTRACT: We measured and determined the factors associated with long-term generic quality-of-life (QOL) changes in human bladder cancer patients. We utilized the World Health Organization QOL-Brief questionnaire to assess consecutive patients' QOL at outpatient clinics of our hospital. A mixed-effects model was constructed to investigate the determinants of QOL changes according to each domain and individual item after controlling for demographic and clinical factors, as well as the effect of radical cystectomy. We also applied a kernel smoothing method to describe the long-term dynamic changes after the first definite treatment. In total, 1185 repeated measurements were collected from 343 bladder cancer patients. The mixed-effects models demonstrated that marital status, monthly income, and comorb

SUBMITTER: Tsai YS 

PROVIDER: S-EPMC8658139 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature