Tris-(2-pyridyl)-pyrazolyl Borate Zinc(II) Complexes: Synthesis, DNA/Protein Binding and In Vitro Cytotoxicity Studies.

ABSTRACT: Zn(II) complexes bearing tris[3-(2-pyridyl)-pyrazolyl] borate (Tp^py) ligand (1-3) was synthesized and examined by spectroscopic and analytical tools. Mononuclear [Tp^pyZnCl] (1) has a Zn(II) centre with one arm (pyrazolyl-pyridyl) dangling outside the coordination sphere which is a novel finding in Tp^pyZn(II) chemistry. In complex [Tp^pyZn(H₂O)][BF₄] (2) hydrogen bonding interaction of aqua moiety stabilizes the dangling arm. In addition, solution state behaviour of complex 1 confirms the tridentate binding mode and reactivity studies show the exogenous axial substituents used to form the [Tp^pyZnN₃] (3). The complexes (1-3) were tested for their abil

SUBMITTER: Narwane M 

PROVIDER: S-EPMC8659194 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature