Ontology highlight
ABSTRACT:
SUBMITTER: Filippov SK
PROVIDER: S-EPMC8659838 | biostudies-literature | 2021 Nov
REPOSITORIES: biostudies-literature
Filippov Sergey K SK Khusnutdinov Ramil R RR Inham Wali W Liu Chang C Nikitin Dmitry O DO Semina Irina I II Garvey Christopher J CJ Nasibullin Shamil F SF Khutoryanskiy Vitaliy V VV Zhang Hongbo H Moustafine Rouslan I RI
Polymers 20211130 23
The choice of drug delivery carrier is of paramount importance for the fate of a drug in a human body. In this study, we have prepared the hybrid nanoparticles composed of FDA-approved Eudragit L100-55 copolymer and polymeric surfactant Brij98 to load haloperidol-an antipsychotic hydrophobic drug used to treat schizophrenia and many other disorders. This platform shows good drug-loading efficiency and stability in comparison to the widely applied platforms of mesoporous silica (MSN) and a metal- ...[more]