Dietary determinants of postprandial blood glucose control in adults with type 1 diabetes on a hybrid closed-loop system.

ABSTRACT:

Aims/hypothesis

The aim of this work was to assess the relationship between meal nutrients and postprandial blood glucose response (PGR) in individuals with type 1 diabetes on a hybrid closed-loop system (HCLS).

Methods

The dietary composition of 1264 meals (398 breakfasts, 441 lunches and 425 dinners) was assessed by 7-day food records completed by 25 individuals with type 1 diabetes on HCLSs (12 men/13 women, mean ± SD age 40 ± 12 years, mean ± SD HbA_1c 51 ± 10 mmol/mol [6.9 ± 0.2%]). For each meal, PGR (continuous glucose monitoring metrics, glucose incremental AUCs) and insulin doses (pre-meal boluses, post-meal microboluses automatically delivered by the pump and adjustment boluses) over 6 h were evaluated.

Results

Breakfast, lunch and dinner significa

SUBMITTER: Vetrani C 

PROVIDER: S-EPMC8660714 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature