Volatile organic compounds as a potential screening tool for neoplasm of the digestive system: a meta-analysis.

ABSTRACT: This meta-analysis was aimed to estimate the diagnostic performance of volatile organic compounds (VOCs) as a potential novel tool to screen for the neoplasm of the digestive system. An integrated literature search was performed by two independent investigators to identify all relevant studies investigating VOCs in diagnosing neoplasm of the digestive system from inception to 7th December 2020. STATA and Revman software were used for data analysis. The methodological quality of each study was assessed using the Quality Assessment of Diagnostic Accuracy Studies tool. A bivariate mixed model was used and meta-regression and subgroup analysis were performed to identify possible sources of heterogeneity. A total of 36 studies comprised of 1712 cases of neoplasm and 3215 controls were included

SUBMITTER: Wang L 

PROVIDER: S-EPMC8660806 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature