Tea crude extracts effectively inactivate severe acute respiratory syndrome coronavirus 2.

ABSTRACT: It is well known that black and green tea extracts, particularly polyphenols, have antimicrobial activity against various pathogenic microbes including viruses. However, there is limited data on the antiviral activity against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which emerged rapidly in China in late 2019 and which has been responsible for coronavirus disease 2019 (COVID-19) pandemic globally. In this study, 20 compounds and three extracts were obtained from black and green tea and found that three tea extracts showed significant antiviral activity against SARS-CoV-2, whereby the viral titre decreased about 5 logs TCID₅₀ per ml by 1·375 mg ml^-1 black tea extract and two-fold diluted tea bag infusion obtained from black tea when incubated at 25

SUBMITTER: Ishimoto K 

PROVIDER: S-EPMC8661916 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature