Modelling direct and herd protection effects of vaccination against the SARS-CoV-2 Delta variant in Australia.

ABSTRACT:

Objectives

To analyse the outcomes of COVID-19 vaccination by vaccine type, age group eligibility, vaccination strategy, and population coverage.

Design

Epidemiologic modelling to assess the final size of a COVID-19 epidemic in Australia, with vaccination program (Pfizer, AstraZeneca, mixed), vaccination strategy (vulnerable first, transmitters first, untargeted), age group eligibility threshold (5 or 15 years), population coverage, and pre-vaccination effective reproduction number ( Reffv¯ ) for the SARS-CoV-2 Delta variant as factors.

Main outcome measures

Numbers of SARS-CoV-2 infections; cumulative hospitalisations, deaths, and years of life lost.

Results

Assuming Reffv¯ = 5, the current mixed vaccination program (vaccinating people aged 60 or more with the

SUBMITTER: McBryde ES 

PROVIDER: S-EPMC8662033 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature