Patterns of Fetal and Infant Growth and Brain Morphology at Age 10 Years.

ABSTRACT:

Importance

Preterm birth and low birth weight are associated with brain developmental and neurocognitive outcomes in childhood; however, not much is known about the specific critical periods in fetal life and infancy for these outcomes.

Objective

To examine the associations of fetal and infant growth patterns with brain morphology in children at school age.

Design, setting, and participants

This population-based, prospective cohort study was conducted from February 1 to April 16, 2021, as a part of the Generation R Study in Rotterdam, the Netherlands. The study included 3098 singleton children born between April 1, 2002, and January 31, 2006.

Exposures

Fetal weight was estimated in the second and third trimesters of pregnancy by ultrasonography. Infant weight w

SUBMITTER: Silva CCV 

PROVIDER: S-EPMC8662367 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature