Phylogenetic Signal, Congruence, and Uncertainty across Bacteria and Archaea.

ABSTRACT: Reconstruction of the Tree of Life is a central goal in biology. Although numerous novel phyla of bacteria and archaea have recently been discovered, inconsistent phylogenetic relationships are routinely reported, and many inter-phylum and inter-domain evolutionary relationships remain unclear. Here, we benchmark different marker genes often used in constructing multidomain phylogenetic trees of bacteria and archaea and present a set of marker genes that perform best for multidomain trees constructed from concatenated alignments. We use recently-developed Tree Certainty metrics to assess the confidence of our results and to obviate the complications of traditional bootstrap-based metrics. Given the vastly disparate number of genomes available for different phyla of bacteria and archaea, we

SUBMITTER: Martinez-Gutierrez CA 

PROVIDER: S-EPMC8662615 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature