Recombination Facilitates Adaptive Evolution in Rhizobial Soil Bacteria.

ABSTRACT: Homologous recombination is expected to increase natural selection efficacy by decoupling the fate of beneficial and deleterious mutations and by readily creating new combinations of beneficial alleles. Here, we investigate how the proportion of amino acid substitutions fixed by adaptive evolution (α) depends on the recombination rate in bacteria. We analyze 3,086 core protein-coding sequences from 196 genomes belonging to five closely related species of the genus Rhizobium. These genes are found in all species and do not display any signs of introgression between species. We estimate α using the site frequency spectrum (SFS) and divergence data for all pairs of species. We evaluate the impact of recombination within each species by dividing genes into three equally sized recombination cla

SUBMITTER: Cavassim MIA 

PROVIDER: S-EPMC8662638 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature