A Co-Association Network Analysis Reveals Putative Regulators for Health-Related Traits in Pigs.

ABSTRACT: In recent years, the increase in awareness of antimicrobial resistance together with the societal demand of healthier meat products have driven attention to health-related traits in livestock production. Previous studies have reported medium to high heritabilities for these traits and described genomic regions associated with them. Despite its genetic component, health- and immunity-related traits are complex and its study by association analysis with genomic markers may be missing some information. To analyse multiple phenotypes and gene-by-gene interactions, systems biology approaches, such as the association weight matrix (AWM), allows combining genome wide association study results with network inference algorithms. The present study aimed to identify gene networks, key regulators and

SUBMITTER: Crespo-Piazuelo D 

PROVIDER: S-EPMC8662732 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature