X-Linked Agammaglobulinemia and COVID-19: Two Case Reports and Review of Literature.

ABSTRACT: Introduction: The Centers for Disease Control and Prevention (CDC) has listed primary immunodeficiency disorders as being predisposed to severe coronavirus disease 2019 (COVID-19). However, patients affected with X-linked agammaglobulinemia (XLA) have shown contrary results. In this study, we present 2 boys in late adolescence from south India with XLA who were infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), as well as a review of cases reported in the literature. Case Presentation: Two patients with XLA had been diagnosed late and were started on regular immunoglobulin prophylaxis only during adolescence. Both of them had developed bronchiectasis, an irreversible suppurative lung disease. However, both patients made an uneventful rec

SUBMITTER: Devassikutty FM 

PROVIDER: S-EPMC8664121 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature