Natural variation in reproductive timing and X-chromosome nondisjunction in Caenorhabditis elegans.

ABSTRACT: Caenorhabditis elegans hermaphrodites first produce a limited number of sperm cells, before their germline switches to oogenesis. Production of progeny then ensues until sperm is depleted. Male production in the self-progeny of hermaphrodites occurs following X-chromosome nondisjunction during gametogenesis, and in the reference strain increases with age of the hermaphrodite parent. To enhance our understanding of the reproductive timecourse in C. elegans, we measured and compared progeny production and male proportion during the early and late reproductive periods of hermaphrodites for 96 wild C. elegans strains. We found that the two traits exhibited natural phenotypic variation with few outliers and a similar reproductive timing pattern as previous reports. Progeny number and male propo

SUBMITTER: Lim J 

PROVIDER: S-EPMC8664432 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature