Cognitive throughput and working memory raw scores consistently differentiate resilient and vulnerable groups to sleep loss.

ABSTRACT:

Study objectives

Substantial individual differences exist in cognitive deficits due to sleep restriction (SR) and total sleep deprivation (TSD), with various methods used to define such neurobehavioral differences. We comprehensively compared numerous methods for defining cognitive throughput and working memory resiliency and vulnerability.

Methods

Forty-one adults participated in a 13-day experiment: 2 baseline, 5 SR, 4 recovery, and one 36 h TSD night. The Digit Symbol Substitution Test (DSST) and Digit Span Test (DS) were administered every 2 h. Three approaches (Raw Score [average SR performance], Change from Baseline [average SR minus average baseline performance], and Variance [intraindividual variance of SR performance]), and six thresholds (±1 standard deviation, and

SUBMITTER: Brieva TE 

PROVIDER: S-EPMC8664585 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature