Impact of Expanded Hemodialysis Using Medium Cut-off Dialyzer on Quality of Life: Application of Dynamic Patient-Reported Outcome Measurement Tool.

ABSTRACT:

Rationale & objective

Current hemodialysis (HD) treatments have limited ability to clear larger-molecular-weight uremic toxins. Retention is associated with increased symptom burden, low health-related quality of life (HRQoL), and high mortality. Improved clearance, using novel medium cut-off dialyzers, termed expanded HD (HDx), may be associated with improved subjective experience. We have previously developed a dynamic patient-reported outcome measure (PROM) instrument to allow iterative recording to better appreciate the overall burden of disease and assess the impact of therapy changes.

Study design

Single-center interventional pilot study.

Setting & participants

28 patients established on maintenance HD, London, Ontario, Canada.

Intervention

Initial study

SUBMITTER: Penny JD 

PROVIDER: S-EPMC8664707 | biostudies-literature | 2021 Nov-Dec

REPOSITORIES: biostudies-literature