New means, new measures: assessing prescription drug-seeking indicators over 10 years of the opioid epidemic.

ABSTRACT:

Background and aims

Prescription drug-seeking (PDS) from multiple prescribers is a primary means of obtaining prescription opioids; however, PDS behavior has probably evolved in response to policy shifts, and there is little agreement about how to operationalize it. We systematically compared the performance of traditional and novel PDS indicators.

Design

Longitudinal study using a de-identified commercial claims database.

Setting

United States, 2009-18.

Participants

A total of 318 million provider visits from 21.5 million opioid-prescribed patients.

Measurements

We applied binary classification and generalized linear models to compare predictive accuracy and average marginal effect size predicting future opioid use disorder (OUD), overdose and high morp

SUBMITTER: Perry BL 

PROVIDER: S-EPMC8664959 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature