Personalized sedation goal for agitated delirium in patients with cancer: Balancing comfort and communication.

ABSTRACT:

Background

Agitated delirium is common and highly distressing. Medications are often needed to reduce agitation, but it is unclear what the desired level of sedation is. This study assessed personalized sedation goals (PSGs) and their predictors for patients in a delirium clinical trial and in clinical vignettes.

Methods

This was a preplanned secondary analysis of a double-blind randomized clinical trial examining the sedative effect of chlorpromazine and/or haloperidol in patients with agitated delirium. At the baseline, caregivers and nurses were independently asked to select the PSG for the trial patient from 5 choices corresponding to Richmond Agitation Sedation Scale (RASS) scores of 0 or higher (no sedation), -1 to -2, -3, -4, and -5 (deep sedation). Respondents also s

SUBMITTER: Hui D 

PROVIDER: S-EPMC8665008 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature