Intracranial vascular imaging detects arterial wall abnormalities in persons with treated HIV infection.

ABSTRACT:

Objective

Although a substantial proportion of ischemic strokes in persons with HIV infection (PWH) is related to large artery disease, studies evaluating elevated cerebrovascular risk in PWH have focused primarily on microvascular disease. We compared the burden of intracranial large artery disease on vessel wall MRI (VW-MRI) in PWH and HIV-uninfected individuals.

Design

Cross-sectional study.

Methods

We recruited antiretroviral therapy-treated PWH with undetectable plasma viral load and HIV-uninfected individuals. All participants were at least 40 years of age and at moderate-to-high cardiovascular risk. We used Poisson and mixed effects logistic regression models to compare the number and associated characteristics of enhancing intracranial arteries on VW-MRI by HI

SUBMITTER: Chow FC 

PROVIDER: S-EPMC8665026 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature