Rapid tool for cell nanoarchitecture integrity assessment.
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ABSTRACT:
SUBMITTER: Gaietta G
PROVIDER: S-EPMC8665072 | biostudies-literature | 2021 Dec
REPOSITORIES: biostudies-literature
Publications
Rapid tool for cell nanoarchitecture integrity assessment.
Gaietta Guido G Swift Mark F MF Volkmann Niels N Hanein Dorit D
Journal of structural biology 20210925 4
With the rapid increase and accessibility of high-resolution imaging technologies of cells, the interpretation of results relies more and more on the assumption that the three-dimensional integrity of the surrounding cellular landscape is not compromised by the experimental setup. However, the only available technology for directly probing the structural integrity of whole-cell preparations at the nanoscale is electron cryo-tomography, which is time-consuming, costly, and complex. We devised an ...[more]
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