Maternal prenatal selenium levels and child risk of neurodevelopmental disorders: A prospective birth cohort study.

ABSTRACT: Selenium (Se) is an essential trace element involved in various biological processes, including neurodevelopment. Available literature indicates that both Se deficiency and excess may be detrimental to health. It is also known that Se can cross the placenta from maternal to fetal circulation. To date, the role of maternal Se status in child long-term neurodevelopment is largely unexplored. This study investigated the temporal and dose-response associations between maternal Se status and child risk of neurodevelopmental disorders including autism spectrum disorder (ASD) and attention deficit hyperactivity disorder (ADHD). It consisted of 1550 mother-infant dyads from the Boston Birth Cohort. Maternal red blood cell (RBC) Se levels were measured in samples collected within 72 h of delivery (

SUBMITTER: Lee ASE 

PROVIDER: S-EPMC8665097 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature