Formation of a ZnO nanorods-patterned coating with strong bactericidal capability and quantitative evaluation of the contribution of nanorods-derived puncture and ROS-derived killing.

ABSTRACT: To endow Ti-based orthopedic implants with strong bactericidal activity, a ZnO nanorods-patterned coating (namely ZNR) was fabricated on Ti utilizing a catalyst- and template-free method of micro-arc oxidation (MAO) and hydrothermal treatment (HT). The coating comprises an outer layer of ZnO nanorods and a partially crystallized inner layer with nanocrystalline TiO₂ and Zn₂TiO₄ embedded amorphous matrix containing Ti, O and Zn. During HT, Zn²⁺ ions contained in amorphous matrix of the as-MAOed layer migrate to surface and react with OH^- in hydrothermal solution to form ZnO nuclei growing in length at expense of the migrated Zn²⁺. ZNR exhibits intense bactericidal activity against the adhered and planktonic S. aureus in vi

SUBMITTER: Ye J 

PROVIDER: S-EPMC8665260 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature