Anatomy and histomorphology of the flexor digitorum profundus enthesis: functional implications for tissue engineering and surgery.

ABSTRACT:

Background

The enthesis possesses morphological adaptations across the soft-hard tissue junction which are not fully restored during surgical avulsion repairs. This loss of anatomical structure, highly related to function, contributes to poor clinical outcomes. Investigating the native macro- and micro-structure of a specific enthesis can provide functional and biomechanical insights to develop specialised, novel tissue-engineered therapeutic options and potentially improve current surgical treatments for avulsion injuries.

Methods

This study examines the anatomy and histomorphology of the flexor digitorum profundus (FDP) enthesis in 96 fresh-frozen human cadaveric fingers, quantitatively and qualitatively analyzing the shape, size, angle of tendon fibres and histological ar

SUBMITTER: Mortimer JW 

PROVIDER: S-EPMC8665545 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature