Comparative Proteome Analysis Indicates The Divergence between The Head and Tail Regeneration in Planarian.

ABSTRACT:

Objective

Even a small fragment from the body of planarian can regenerate an entire animal, implying that the different fragments from this flatworm eventually reach the same solution. In this study, our aim was to reveal the differences and similarities in mechanisms between different regenerating fragments from this worm.

Materials and methods

In this experimental study, we profiled the dynamic proteome of regenerating head and tail to reveal the differences and similarities between different regenerating fragments using 2-DE combined with MALDITOF/ TOF MS.

Results

Proteomic profiles of head and tail regeneration identified a total of 516 differential expressed proteins (DEPs) and showed a great difference in quantity and fold changes of proteome profiles between th

SUBMITTER: Chen X 

PROVIDER: S-EPMC8665983 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature