Oxygen atom transfer promoted nitrate to nitric oxide transformation: a step-wise reduction of nitrate → nitrite → nitric oxide.

ABSTRACT: Nitrate reductases (NRs) are molybdoenzymes that reduce nitrate (NO₃ ^-) to nitrite (NO₂ ^-) in both mammals and plants. In mammals, the salival microbes take part in the generation of the NO₂ ^- from NO₃ ^-, which further produces nitric oxide (NO) either in acid-induced NO₂ ^- reduction or in the presence of nitrite reductases (NiRs). Here, we report a new approach of VCl₃ (V³⁺ ion source) induced step-wise reduction of NO₃ ^- in a Co^II-nitrato complex, [(12-TMC)Co^II(NO₃ ^-)]⁺ (2,{Co^II-NO₃ ^-}), to a Co^III-nitrosyl complex, [(12-TMC)Co^III

SUBMITTER: Kulbir 

PROVIDER: S-EPMC8666158 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature