Symptoms Burden and Health-related Quality of Life in Chinese Patients with Primary Biliary Cholangitis.

ABSTRACT:

Background and aims

Primary biliary cholangitis (PBC) is a chronic liver disease that negatively affects the health-related quality of life (HRQoL) of patients. Furthermore, the HRQoL of Chinese patients has been neglected for a long time. The present study aimed to assess the HRQoL of Chinese patients with PBC and explore the clinical variables correlating to the improvement of itch and fatigue.

Methods

This was an observational, cross-sectional study. The PBC-40 and itch numerical rating scales were used to evaluate the symptoms and HRQoL of patients.

Results

A total of 383 patients were recruited, and 86.4% were female, with a median age of 55 years (range: 49-63 years). We found that females had significantly higher scores than males in symptoms (p=0.033) a

SUBMITTER: Liu Y 

PROVIDER: S-EPMC8666377 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature