Body mass index, not race, may be associated with an alteration in early embryo morphokinetics during in vitro fertilization.

ABSTRACT:

Objective

To assess the relationship between maternal body mass index (BMI) and embryo morphokinetics on time-lapse microscopy (TLM).

Design

Retrospective cohort study.

Methods

All IVF cycles between June 2015 and April 2017 were reviewed. Female BMI prior to egg retrieval was collected through chart review. BMI (kg/m²) classification included underweight (< 18.5), normal weight (18.5-25), overweight (25-30), and obese (≥ 30). Embryos' morphokinetic parameters were assessed with TLM and included time to syngamy, 2-cell, 3-cell, 4-cell, and 8-cell. A generalized linear mixed model was used to control for potential confounders and multiple embryos resulting from a single IVF cycle.

Results

A total of 2150 embryos from 589 IVF cycles were reviewed and i

SUBMITTER: Kassi LA 

PROVIDER: S-EPMC8666401 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature