Validation of secondary peristalsis classification using FLIP panometry in 741 subjects undergoing manometry.

ABSTRACT:

Background and aims

This study aimed to systematically evaluate a classification scheme of secondary peristalsis using functional luminal imaging probe (FLIP) panometry through comparison with primary peristalsis on high-resolution manometry (HRM).

Methods

706 adult patients that completed FLIP and HRM for primary esophageal motility evaluation and 35 asymptomatic volunteers ("controls") were included. Secondary peristalsis, that is, contractile responses (CRs), was classified on FLIP panometry by the presence and pattern of contractility as normal (NCR), borderline (BCR), impaired/disordered (IDCR), absent (ACR), or spastic-reactive (SRCR). Primary peristalsis on HRM was assessed according to the Chicago Classification.

Results

All 35 of the controls had antegrade co

SUBMITTER: Carlson DA 

PROVIDER: S-EPMC8666463 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature