Associations between LMO1 gene polymorphisms and central nervous system tumor susceptibility.

ABSTRACT:

Importance

LIM domain only 1 (LMO1) gene polymorphisms were previously found to be implicated in the risk of several cancers. No available studies were performed regarding the predisposing effect of LMO1 gene single nucleotide polymorphisms (SNPs) on central nervous system (CNS) tumor risk.

Objective

We aimed to determine whether the LMO1 gene SNPs were associated with the risk of CNS tumor by applying a case-control study with 191 cases and 248 controls in China.

Methods

The contributions of LMO1 gene SNPs to the risk of CNS tumor was evaluated by multinomial logistic regression.

Results

Based on the calculations of odds ratio (OR) and 95% confidence interval (CI), we failed to detect a significant relationship between

SUBMITTER: Lin H 

PROVIDER: S-EPMC8666933 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature