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ABSTRACT: Background
No comparisons between mortality from opioids in children and teenagers and opioid prescription patterns have been made in England.Aim
To investigate if an association exists between mortality rates from opioid poisoning in persons aged 19 years old and under and community opioid prescription in England.Methods
A retrospective analysis was undertaken for 2016 to 2019, comparing community opioid prescriptions and mortality rates from opioid poisoning.Results
The number of opioid prescriptions decreased over the study period (- 2.4%, p < 0.001). Most deaths due to opioid poisoning in children and teenagers were seen in those under one year old and those aged between 15 and 19 years old (Kruskal-Wallis: p = 0.12; Dunn's test: p = 0.01). Deaths in all age ranges did not change significantly (Poisson Regression Analysis: p > 0.05).Conclusion
Despite the reduction in community opioid prescriptions, there was no decrease in the number of deaths in children and teenagers due to opioid poisoning.
SUBMITTER: Cranfield E
PROVIDER: S-EPMC8667418 | biostudies-literature | 2021 Dec
REPOSITORIES: biostudies-literature
Cranfield Elise E Ashcroft Elizabeth E Forget Patrice P
BMC pediatrics 20211213 1
<h4>Background</h4>No comparisons between mortality from opioids in children and teenagers and opioid prescription patterns have been made in England.<h4>Aim</h4>To investigate if an association exists between mortality rates from opioid poisoning in persons aged 19 years old and under and community opioid prescription in England.<h4>Methods</h4>A retrospective analysis was undertaken for 2016 to 2019, comparing community opioid prescriptions and mortality rates from opioid poisoning.<h4>Results ...[more]