Cocculus hirsutus-Derived Phytopharmaceutical Drug Has Potent Anti-dengue Activity.

ABSTRACT: Dengue is a serious public health concern worldwide, with ∼3 billion people at risk of contracting dengue virus (DENV) infections, with some suffering severe consequences of disease and leading to death. Currently, there is no broad use vaccine or drug available for the prevention or treatment of dengue, which leaves only anti-mosquito strategies to combat the dengue menace. The present study is an extension of our earlier study aimed at determining the in vitro and in vivo protective effects of a plant-derived phytopharmaceutical drug for the treatment of dengue. In our previous report, we had identified a methanolic extract of aerial parts of Cissampelos pareira to exhibit in vitro and in vivo anti-dengue activity against all the four DENV serotypes. Th

SUBMITTER: Shukla R 

PROVIDER: S-EPMC8667597 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature