Rapid screening and identification of viral pathogens in metagenomic data.

ABSTRACT:

Background

Virus screening and viral genome reconstruction are urgent and crucial for the rapid identification of viral pathogens, i.e., tracing the source and understanding the pathogenesis when a viral outbreak occurs. Next-generation sequencing (NGS) provides an efficient and unbiased way to identify viral pathogens in host-associated and environmental samples without prior knowledge. Despite the availability of software, data analysis still requires human operations. A mature pipeline is urgently needed when thousands of viral pathogen and viral genome reconstruction samples need to be rapidly identified.

Results

In this paper, we present a rapid and accurate workflow to screen metagenomics sequencing data for viral pathogens and other compositions, as well as enable a r

SUBMITTER: Song S 

PROVIDER: S-EPMC8668262 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature