Evidence of Nasal Cooling and Sensory Impairments Driving Patient Symptoms With Septal Deviation.

ABSTRACT:

Objectives/hypothesis

About 260,000 septoplasties are performed annually in the US to address nasal septal deviation (NSD). Yet, we do not consistently understand what aspects of NSD result in symptoms.

Study design

Blinded cohort study.

Methods

Two fellowship-trained surgeons blindly reviewed computerized tomography (CTs) of 10 confirmed NSD patients mixed with 36 healthy controls. All patients were correctly identified, however, 24/36 controls were falsely identified by both surgeons as patients (33.3% specificity), which were grouped as asymptomatic NSD (aNSD), while the remaining controls as non-NSD (healthy). Acoustic rhinometry, rhinomanometry, individual CT-based computational fluid dynamics and nasal sensory testing were applied to address the puzzling questio

SUBMITTER: Malik J 

PROVIDER: S-EPMC8669045 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature